ING1 Antikörper (C-Term)

Produktnummer ABIN2784213

Der Kaninchen Polyklonal anti-ING1 Antikörper wird verwendet zum Nachweis von ING1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Zebrafisch (Danio rerio), Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für ING1 Antikörper (C-Term) (ABIN2784213)

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Zebrafisch (Danio rerio), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ING1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ING1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: ING1 Antibody - C-terminal region

Sequenz: EKKAKTSKKK KRSKAKAERE ASPADLPIDP NEPTYCLCNQ VSYGEMIGCD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ING1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ING1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8103042

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ING1

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Andere Bezeichnung: ING1

Hintergrund:

Background Information: ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene Name: Inhibitor of growth family, member 1

Alternative Symbols: p33, p47, p33ING1, p24ING1c, p33ING1b, p47ING1a

Protein Name: Inhibitor of growth protein 1

Molekulargewicht: 32kDa

Gen-ID: 3621

NCBI Accession: NP_937862

UniProt: Q5T9H0

Pathways: Protein targeting to Nucleus, Autophagie