CDC25A Antikörper (N-Term)
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- Target Alle CDC25A Antikörper anzeigen
- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CDC25A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
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Rabbit Polyclonal antibody to CDC25A (cell division cycle 25 homolog A (S. pombe))
CDC25A antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the N-terminus region of human CDC25A. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product CDC25A Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: H1299 , MCF-7
Validation: Orthogonal
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
- Andere Bezeichnung
- cell division cycle 25A (CDC25A Produkte)
- Synonyme
- cdc25a2 antikoerper, cdc25A antikoerper, sb:cb317 antikoerper, CDC25A2 antikoerper, D9Ertd393e antikoerper, cell division cycle 25A antikoerper, cell division cycle 25B antikoerper, cell division cycle 25A S homeolog antikoerper, CDC25A antikoerper, cdc25a antikoerper, cdc25b antikoerper, Cdc25a antikoerper, cdc25a.S antikoerper
- Hintergrund
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CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
- 59 kDa
- Gen-ID
- 993
- UniProt
- P30304
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases, M Phase
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