MAPT Antikörper
Kurzübersicht für MAPT Antikörper (ABIN2854882)
Target
Alle MAPT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
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Rabbit Polyclonal antibody to Tau (microtubule-associated protein tau)
Tau antibody -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human Tau. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: IMR32 , SK-N-AS , mouse brain , SK-N-SH
Validation: Comparison, KO/KD, Orthogonal
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.34 mg/mL
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Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- MAPT (Microtubule-Associated Protein tau (MAPT))
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Andere Bezeichnung
- microtubule associated protein tau
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Hintergrund
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This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Cellular Localization: Cytoplasm , cytosol , Cell membrane, Peripheral membrane protein, Cytoplasmic side , cytoskeleton , Cell projection , axon -
Molekulargewicht
- 79 kDa
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Gen-ID
- 4137
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UniProt
- P10636
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Pathways
- MAPK Signalweg, Microtubule Dynamics, M Phase, Regulation of Cell Size
Target
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