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MAPT Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MAPT in WB, IF, ICC und IHC (p). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN2854882

Kurzübersicht für MAPT Antikörper (ABIN2854882)

Target

Alle MAPT Antikörper anzeigen
MAPT (Microtubule-Associated Protein tau (MAPT))

Reaktivität

  • 246
  • 120
  • 115
  • 15
  • 7
  • 6
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 222
  • 31
  • 7
  • 2
  • 1
Kaninchen

Klonalität

  • 197
  • 66
Polyklonal

Konjugat

  • 216
  • 17
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Dieser MAPT Antikörper ist unkonjugiert

Applikation

  • 218
  • 141
  • 90
  • 39
  • 37
  • 28
  • 16
  • 7
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse

KO Validated
  • Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Rabbit Polyclonal antibody to Tau (microtubule-associated protein tau)
    Tau antibody

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human Tau. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: IMR32 , SK-N-AS , mouse brain , SK-N-SH

    Validation: Comparison, KO/KD, Orthogonal

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.34 mg/mL

    Buffer

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    MAPT (Microtubule-Associated Protein tau (MAPT))

    Andere Bezeichnung

    microtubule associated protein tau

    Hintergrund

    This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

    Cellular Localization: Cytoplasm , cytosol , Cell membrane, Peripheral membrane protein, Cytoplasmic side , cytoskeleton , Cell projection , axon

    Molekulargewicht

    79 kDa

    Gen-ID

    4137

    UniProt

    P10636

    Pathways

    MAPK Signalweg, Microtubule Dynamics, M Phase, Regulation of Cell Size
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