Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

EGFR Antikörper (C-Term)

Name: EGFR Antikörper (C-Term)
Brand: antibodies-online
SKU: ABIN2854754
Price: 659.23 EUR
Availability: InStock

KO Validated EGFR Reaktivität: Human WB, IF, FACS, IHC (p), IP, ICC Wirt: Kaninchen Polyclonal unconjugated

WB Image Sample (30 ug of whole cell lysate) A: A431 5% SDS PAGE antibody diluted at 1:10000 (EGFR Antikörper (C-Term))

ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed A431, using EGFR, antibody (Green) at 1:1000 dilution. (EGFR Antikörper (C-Term))

IP Image EGFR antibody [C2C3], C-term immunoprecipitates EGFR protein in IP experiments. (EGFR Antikörper (C-Term))

IHC-P Image EGFR antibody [C2C3], C-term detects EGFR protein at membrane on human gastric cancer by immunohistochemical analysis. (EGFR Antikörper (C-Term))

IHC

5 Abbildungen

Produktnummer ABIN2854754

Datenblatt (PDF)

Target Alle EGFR Antikörper anzeigen

EGFR (Epidermal Growth Factor Receptor (EGFR))
Bindungsspezifität
39

38

31

30

30

28

27

26

25

22

21

18

16

16

16

15

15

15

11

11

10

9

9

9

8

8

7

6

5

5

5

4

4

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3
C-Term
Reaktivität
759

299

287

25

25

24

20

14

8

3

2

2

1

1

1

1

1

1
Human
Wirt
580

178

14

13

5

2

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
542

247

2
Polyklonal
Konjugat
413

58

29

22

20

18

18

17

16

16

16

12

10

10

10

10

10

10

10

10

10

8

8

5

4

4

4

4

4

2

1

1

1

1

1

1
Dieser EGFR Antikörper ist unkonjugiert
Applikation
537

250

151

151

127

102

98

92

82

45

37

34

34

19

11

8

6

4

4

3

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Spezifität

IP/MS validation was supported by references (PMID:30377372)

Kreuzreaktivität

Human, Maus, Ratte

Produktmerkmale

Rabbit Polyclonal antibody to EGFR (epidermal growth factor receptor)
EGFR antibody [C2C3], C-term

Aufreinigung

Purified by antigen-affinity chromatography.

Güteklasse

KO Validated

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human EGFR. The exact sequence is proprietary.

Isotyp

IgG

Top Product

Discover our top product EGFR Primärantikörper
anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody
EGFR Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 7A6F12 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 888-1210) antibody
EGFR Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C4 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 1163-1191), (C-Term) antibody
EGFR Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal 688CT33-1-3 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR Reaktivität: Human, Maus, Ratte, Schwein, Affe, Rind (Kuh), Huhn, Hund, Pferd, Kaninchen, Meerschweinchen, Avian, Cat, Esel, Ziege, Hamster, Schaf WB Wirt: Ziege Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody
EGFR Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 5E10D3 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer1026) antibody
EGFR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibody
EGFR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer695) antibody
EGFR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 1021-1210) antibody
EGFR Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR Reaktivität: Human, Ratte WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare

Positive Control: A431
Validation: IP/MS, KO/KD, Orthogonal

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.28 mg/mL

Buffer

1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Target

EGFR (Epidermal Growth Factor Receptor (EGFR))

Andere Bezeichnung

epidermal growth factor receptor (EGFR Produkte)

Hintergrund

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Cellular Localization: Cell membrane, Single-pass type I membrane protein , Isoform 2: Secreted

Molekulargewicht

134 kDa

Gen-ID

1956

UniProt

P00533

Pathways

NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine