CYLD Antikörper (C-Term)
Kurzübersicht für CYLD Antikörper (C-Term) (ABIN2854660)
Target
Alle CYLD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Kreuzreaktivität
- Xenopus tropicalis, Rind (Kuh)
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Kreuzreaktivität (Details)
- Xenopus Tropicalis (100 %), Bovine (100 %)
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Produktmerkmale
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Rabbit Polyclonal antibody to CYLD (cylindromatosis (turban tumor syndrome))
CYLD antibody -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CYLD. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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Kommentare
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Positive Control: HepG2 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
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Andere Bezeichnung
- CYLD
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Hintergrund
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This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Cellular Localization: Cytoplasm , perinuclear region -
Molekulargewicht
- 107 kDa
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Gen-ID
- 1540
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Pathways
- Apoptose, Activation of Innate immune Response
Target
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