NOTCH3 Antikörper (C-Term)
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- Target Alle NOTCH3 Antikörper anzeigen
- NOTCH3 (Notch 3 (NOTCH3))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NOTCH3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Maus, Ratte (Rattus)
- Kreuzreaktivität (Details)
- Mouse (100 %), Rat (100 %)
- Produktmerkmale
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Rabbit polyclonal antibody to Notch 3 (Notch homolog 3 (Drosophila))
Notch 3 antibody [C3], C-term - Aufreinigung
- Affinity purified by Protein A.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Notch 3. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product NOTCH3 Primärantikörper
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- Applikationshinweise
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
- Kommentare
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Positive Control: HeLa
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 5.26 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- NOTCH3 (Notch 3 (NOTCH3))
- Andere Bezeichnung
- Notch 3 (NOTCH3 Produkte)
- Synonyme
- CADASIL antikoerper, CASIL antikoerper, IMF2 antikoerper, AW229011 antikoerper, N3 antikoerper, hpbk antikoerper, fa14b08 antikoerper, notch5 antikoerper, wu:fa14b08 antikoerper, notch 3 antikoerper, NOTCH3 antikoerper, Notch3 antikoerper, notch3 antikoerper
- Hintergrund
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This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Cellular Localization: Cell membrane, Single-pass type I membrane protein , Notch 3 intracellular domain: Nucleus - Molekulargewicht
- 244 kDa
- Gen-ID
- 4854
- Pathways
- Notch Signalweg
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