IL5RA Antikörper

Produktnummer ABIN2854437

Dieses Anti-IL5RA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IL5RA in WB. Geeignet für Human.

Kurzübersicht für IL5RA Antikörper (ABIN2854437)

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL5RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL5RA Antikörper

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to IL5 Receptor alpha (interleukin 5 receptor, alpha)
IL5 Receptor alpha antibody [N1C2]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human IL5 Receptor alpha. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HCT116

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu IL5RA

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Andere Bezeichnung: interleukin 5 receptor subunit alpha

Hintergrund: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.

Cellular Localization: Membrane, Single-pass type I membrane protein

Molekulargewicht: 48 kDa

Gen-ID: 3568

UniProt: Q01344

Pathways: JAK-STAT Signalweg