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IL5RA Antikörper

Dieses Anti-IL5RA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IL5RA in WB. Geeignet für Human.
Produktnummer ABIN2854437

Kurzübersicht für IL5RA Antikörper (ABIN2854437)

Target

Alle IL5RA Antikörper anzeigen
IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Reaktivität

  • 74
  • 38
  • 7
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 71
  • 7
  • 1
Kaninchen

Klonalität

  • 70
  • 6
  • 2
Polyklonal

Konjugat

  • 38
  • 8
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser IL5RA Antikörper ist unkonjugiert

Applikation

  • 65
  • 29
  • 29
  • 16
  • 13
  • 13
  • 8
  • 8
  • 5
  • 3
  • 2
  • 2
Western Blotting (WB)
  • Kreuzreaktivität

    Human

    Produktmerkmale

    Rabbit Polyclonal antibody to IL5 Receptor alpha (interleukin 5 receptor, alpha)
    IL5 Receptor alpha antibody [N1C2]

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human IL5 Receptor alpha. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: HCT116

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

    Andere Bezeichnung

    interleukin 5 receptor subunit alpha

    Hintergrund

    The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.

    Cellular Localization: Membrane, Single-pass type I membrane protein

    Molekulargewicht

    48 kDa

    Gen-ID

    3568

    UniProt

    Q01344

    Pathways

    JAK-STAT Signalweg
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