MUTYH Antikörper (Center)

Produktnummer ABIN2854424

Der Kaninchen Polyklonal Anti-MUTYH-Antikörper wurde für WB validiert. Er ist geeignet, MUTYH in Proben von Human und Maus zu detektieren.

Kurzübersicht für MUTYH Antikörper (Center) (ABIN2854424)

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUTYH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MUTYH Antikörper

Bindungsspezifität: Center

Produktmerkmale: Rabbit polyclonal antibody to MYH (mutY homolog (E. coli))
MUTYH antibody [N3C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MUTYH. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , NIH-3T3

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.39 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu MUTYH

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Andere Bezeichnung: MUTYH

Hintergrund: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Nucleus

Molekulargewicht: 60 kDa

Gen-ID: 4595

Pathways: DNA Reparatur