RAD23A Antikörper (Center)

Produktnummer ABIN2854373

Der Kaninchen Polyklonal Anti-RAD23A-Antikörper wurde für WB validiert. Er ist geeignet, RAD23A in Proben von Human zu detektieren.

Kurzübersicht für RAD23A Antikörper (Center) (ABIN2854373)

Target: RAD23A (RAD23 Homolog A (RAD23A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD23A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RAD23A Antikörper

Bindungsspezifität: Center

Kreuzreaktivität: Maus, Rind (Kuh)

Kreuzreaktivität (Details): Mouse (98 %), Bovine (98 %)

Produktmerkmale: Rabbit polyclonal antibody to hHR23A (RAD23 homolog A (S. cerevisiae))
Rad23A antibody [N3C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Rad23A. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: A431 , H1299 , HeLa

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.76 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu RAD23A

Target: RAD23A (RAD23 Homolog A (RAD23A))

Andere Bezeichnung: Rad23A

Hintergrund: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Cellular Localization: Nucleus

Molekulargewicht: 40 kDa

Gen-ID: 5886

Pathways: DNA Reparatur