Integrin Alpha2b Antikörper (C-Term)

Produktnummer ABIN2854318

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Integrin Alpha2b in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Integrin Alpha2b Antikörper (C-Term) (ABIN2854318)

Target: Integrin Alpha2b (CD41)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Integrin Alpha2b Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Integrin Alpha2b Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Rind (Kuh)

Kreuzreaktivität (Details): Bovine (80 %)

Produktmerkmale: Rabbit Polyclonal antibody to CD41
CD41 antibody [C1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human CD41. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: K562

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.66 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Andere Bezeichnung: CD41

Hintergrund: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Cellular Localization: Membrane, Single-pass type I membrane protein

Molekulargewicht: 113 kDa

Gen-ID: 3674

Pathways: Integrin Complex