Prostate Specific Antigen Antikörper

Produktnummer ABIN2853633

Dieser Maus Monoklonal Antikörper detektiert spezifisch Prostate Specific Antigen in WB, IHC (p), IHC (fro) und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Prostate Specific Antigen Antikörper (ABIN2853633)

Target: Prostate Specific Antigen (PSA)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Prostate Specific Antigen Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: CHYH2

Produktdetails anti-Prostate Specific Antigen Antikörper

Spezifität: This antibody detects normal prostate, benign prostate hyperplasia and prostate malignant carcinoma.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Human Prostate Specific Antigen

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: Concentration of 10 μg/mL MAb will allow visualization of 1 μg/lane of humanPSA. Immunohistochemistry-formalin-fixed paraffin embedded and frozen tissue sections usingABC immunoperoxidase assay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with double distillated water to a final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.0 without preservatives

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Details zu Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Andere Bezeichnung: Kallikrein-3 / PSA / KLK3

Hintergrund: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates two transcript variants encoding different isoforms. Additional transcript variants have been described, but it is unclear if these transcripts are normally expressed or if they are specific to benign or malignant tumors.Synonyms: Gamma-seminoprotein, P-30 antigen, Prostate-specific antigen, Semenogelase

Gen-ID: 354

NCBI Accession: NP_001025218

UniProt: P07288

Pathways: Komplementsystem