ATM Antikörper (C-Term)
Kurzübersicht für ATM Antikörper (C-Term) (ABIN363380)
Target
Alle ATM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- Reacts with human and mouse ATM protein
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A fragment of human ATM protein expressed in E.coli. The fragment relates to the C-terminal region (within the last third of the protein sequence)
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Applikationshinweise
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- ICC/IF : 1/100 - IP : 1/100 to 1/500 - WB : 1/500 to 1/1 000 - IHC: 1/100 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 2.5 mg/mL
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Buffer
- PBS, glycerol 50 % , Sodium azide 0.05 %
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C/-80 °C
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Informationen zur Lagerung
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- ATM (Ataxia Telangiectasia Mutated (ATM))
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Andere Bezeichnung
- Serine-Protein Kinase ATM
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Hintergrund
- Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Involved in Cell cycle, DNA damage, DNA repair.
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Gen-ID
- 472
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Pathways
- p53 Signalweg, Apoptose, DNA Reparatur, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
Target
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