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BCL3 Antikörper (Center)

Dieses Anti-BCL3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BCL3 in WB, IF, FACS und IHC (p). Geeignet für Human und Maus. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN653286

Kurzübersicht für BCL3 Antikörper (Center) (ABIN653286)

Target

Alle BCL3 Antikörper anzeigen
BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reaktivität

  • 37
  • 36
  • 6
Human, Maus

Wirt

  • 46
  • 8
  • 5
Kaninchen

Klonalität

  • 48
  • 11
Polyklonal

Konjugat

  • 31
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BCL3 Antikörper ist unkonjugiert

Applikation

  • 45
  • 19
  • 13
  • 13
  • 12
  • 11
  • 10
  • 9
  • 8
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB23954
  • Bindungsspezifität

    • 15
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 249-277, Center

    Spezifität

    This BCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248~277 amino acids from the Center region of human BCL3.

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This BCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 AA from the Central region of human BCL3.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.48 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Gehrke, Wörns, Huber, Hess, Straub, Hövelmeyer, Waisman, Kim, Schuppan, Galle, Schattenberg: "Hepatic B cell leukemia-3 promotes hepatic steatosis and inflammation through insulin-sensitive metabolic transcription factors." in: Journal of hepatology, Vol. 65, Issue 6, pp. 1188-1197, (2018) (PubMed).

  • Target

    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

    Andere Bezeichnung

    BCL3

    Hintergrund

    BCL3 is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers.
    Synonyms: Proto-oncogene BCL3, B-cell lymphoma 3 protein, BCL-3, D19S37, BCL4, BCL3

    Molekulargewicht

    46800 Da

    Gen-ID

    602

    UniProt

    P20749

    Pathways

    NF-kappaB Signalweg, Maintenance of Protein Location, Protein targeting to Nucleus
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