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FAK Antikörper (pSer732) (AbBy Fluor® 594)

Der Kaninchen Polyklonal Anti-FAK-Antikörper wurde für WB, IF (p), IF (cc) und FACS validiert. Er ist geeignet, FAK in Proben von Human und Maus zu detektieren.
Produktnummer ABIN2813047

Kurzübersicht für FAK Antikörper (pSer732) (AbBy Fluor® 594) (ABIN2813047)

Target

Alle FAK (PTK2) Antikörper anzeigen
FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Reaktivität

  • 344
  • 281
  • 214
  • 22
  • 21
  • 17
  • 16
  • 12
  • 8
  • 8
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 345
  • 28
  • 3
  • 2
  • 1
  • 1
Kaninchen

Klonalität

  • 332
  • 48
Polyklonal

Konjugat

  • 176
  • 17
  • 16
  • 12
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 9
  • 7
  • 7
  • 6
  • 6
  • 6
  • 6
  • 1
  • 1
Dieser FAK Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation

  • 308
  • 132
  • 132
  • 120
  • 110
  • 75
  • 68
  • 46
  • 41
  • 34
  • 31
  • 5
  • 3
  • 2
  • 2
  • 2
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 43
    • 36
    • 31
    • 28
    • 24
    • 22
    • 22
    • 21
    • 16
    • 15
    • 13
    • 11
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer732

    Kreuzreaktivität

    Human, Maus

    Homologie

    Rat

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic phosphopeptide derived from human FAK around the phosphorylation site of Tyr732

    Isotyp

    IgG
  • Applikationshinweise

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

    Andere Bezeichnung

    FAK

    Hintergrund

    Synonyms: FAK phospho S732, p-FAK phospho S732, FADK 1, FADK, FAK 1, FAK related non kinase polypeptide, FAK1, Focal adhesion kinase 1, FRNK, pp125FAK, Protein tyrosine kinase 2, Protein Tyrosine Kinase Cytoplasmic, PTK 2, FAK1_HUMAN, Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK.

    Background: Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. [SUBCELLULAR LOCATION] Cell junction, focal adhesion. Cell membrane, Peripheral membrane protein, Cytoplasmic side. Note=Constituent of focal adhesions.

    Gen-ID

    5747

    Pathways

    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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