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beta Catenin Antikörper (AA 661-781) (AbBy Fluor® 594)

CATNB Reaktivität: Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio) WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 594

Produktnummer ABIN2810278

Datenblatt (PDF)

Target Alle beta Catenin (CATNB) Antikörper anzeigen

beta Catenin (CATNB) (Catenin, beta (CATNB))
Bindungsspezifität
43

27

23

20

20

19

17

17

16

16

15

15

8

7

7

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 661-781
Reaktivität
325

231

209

28

22

21

17

17

5

5

5

4

1

1

1

1

1

1

1
Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio)
Wirt
265

60

4

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
256

73

2
Polyklonal
Konjugat
125

21

11

10

9

9

9

9

9

9

9

9

9

9

8

8

6

5

5

5

5

5

4

4

4

4

4

4

1

1

1
Dieser beta Catenin Antikörper ist konjugiert mit AbBy Fluor® 594
Applikation
206

159

119

117

72

68

61

49

35

32

24

9

7

4

2

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität

Human, Maus, Schwein, Ratte, Zebrafisch (Danio rerio)

Homologie

Cow,Sheep,Chicken,Rabbit

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human Beta catenin

Isotyp

IgG

Top Product

Discover our top product CATNB Primärantikörper
anti-Catenin, beta (CATNB) (pSer33), (pSer37) antibody
CATNB Reaktivität: Human, Maus, Ratte WB, FACS, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Catenin, beta (CATNB) (AA 661-781) antibody
CATNB Reaktivität: Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio) WB, FACS, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Catenin, beta (CATNB) (C-Term) antibody
CATNB Reaktivität: Human, Maus, Ratte, Huhn, Rind (Kuh), Hund, Schwein, Kaninchen, Schaf, Affe, Hamster, Avian, Cat, Esel, Ziege, Meerschweinchen, Pferd WB, IF Wirt: Ziege Polyclonal unconjugated

anti-Catenin, beta (CATNB) (C-Term) antibody
CATNB Reaktivität: Human, Zebrafisch (Danio rerio) WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Catenin, beta (CATNB) (pSer33), (pSer37), (pThr41) antibody
CATNB Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Catenin, beta (CATNB) (AA 439-675) antibody
CATNB Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Catenin, beta (CATNB) (AA 439-675) antibody
CATNB Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C901 unconjugated

anti-Catenin, beta (CATNB) antibody
CATNB Reaktivität: Human, Maus, Hamster WB, IP, ICC, ICFC Wirt: Maus Monoclonal EM-22 unconjugated

anti-Catenin, beta (CATNB) antibody
CATNB Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Maus Monoclonal 4A3H3 unconjugated

anti-Catenin, beta (CATNB) (AA 764-781) antibody
CATNB Reaktivität: Human, Maus, Ratte WB, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit

12 months
Target

beta Catenin (CATNB) (Catenin, beta (CATNB))

Andere Bezeichnung

Beta catenin (CATNB Produkte)

Hintergrund

Synonyms: CTNNB, MRD19, armadillo, Catenin beta-1, Beta-catenin, CTNNB1, OK/SW-cl.35, PRO2286
Background: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML.

Gen-ID

1499

UniProt

P35222

Pathways

Peptide Hormone Metabolism