Aurora A Antikörper (AbBy Fluor® 594)

Produktnummer ABIN2810099

Dieses Anti-Aurora A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Aurora A in WB und IF (p). Geeignet für Human, Maus, Ratte, Rind (Kuh) und Schwein.

Kurzübersicht für Aurora A Antikörper (AbBy Fluor® 594) (ABIN2810099)

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aurora A Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Aurora A Antikörper (AbBy Fluor® 594)

Kreuzreaktivität: Rind (Kuh), Human, Maus, Schwein, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Auroa A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Andere Bezeichnung: Aurora A

Hintergrund:

Synonyms: Aurora A Thr288, p-Aurora AT288, AIK, ARK-1, ARK1, AURA, AURKA, Aurora 2, Aurora A, Aurora A, Aurora Family Kinase 1, aurora kinase A, Aurora Related Kinase 1, Aurora-related kinase 1, Aurora/IPL1 Like Kinase, Aurora/IPL1 Related Kinase 1, Aurora/IPL1-related kinase 1, AURORA2, AYK1, BRAK, Breast Tumor Amplied Kinase, Breast tumor-amplied kinase, BTAK, hARK1, IAK, IPL1 Aurora Related Kinase 1, IPL1 Related Kinase, MGC34538, OTTHUMP00000031340, OTTHUMP00000031341, OTTHUMP00000031342, OTTHUMP00000031343, OTTHUMP00000031344, OTTHUMP00000031345, OTTHUMP00000166071, OTTHUMP00000166072, PPP1R47, Protein phosphatase 1, regulatory subunit 47, Serine/threonine kinase 15, Serine/threonine kinase 6, Serine/threonine kinase, Serine/threonine kinase, Serine/threonine-protein kinase 15, Serine/threonine-protein kinase 6, Serine/threonine-protein kinase aurora-A, STK15, STK6, STK6_HUMAN, STK7.

Background: Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.

Gen-ID: 6790

Pathways: Zellzyklus, Asymmetric Protein Localization