TLR8 Antikörper (C-Term)

Produktnummer ABIN2798863

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TLR8 in WB und IHC. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für TLR8 Antikörper (C-Term) (ABIN2798863)

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TLR8 Antikörper

Bindungsspezifität: AA 957-987, C-Term

Verwendungszweck: Rabbit Anti-Mouse Mouse TLR8 (C-term) Antibody

Immunogen: This Mouse TLR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 957-987 amino acids from the C-terminal region of mouse TLR8.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50TLR8 Antibody (E972) for immunohistochemistry. Clinical relevance has not been evaluated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.460 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu TLR8

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Andere Bezeichnung: TLR8

Hintergrund:

Target Description: TLR8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR8 is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

Gene Symbol: Tlr8

Molekulargewicht: 119358 Da

Gen-ID: 170744

UniProt: P58682

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades