RAD51C Antikörper (Center)

Produktnummer ABIN2798838

Dieses Anti-RAD51C-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RAD51C in WB. Geeignet für Human.

Kurzübersicht für RAD51C Antikörper (Center) (ABIN2798838)

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD51C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RAD51C Antikörper

Bindungsspezifität: AA 169-198, Center

Verwendungszweck: Rabbit Anti-Human RAD51C (Center) Antibody

Immunogen: This RAD51C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human RAD51C.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000RAD51C Antibody (Center) .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu RAD51C

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Andere Bezeichnung: RAD51C

Hintergrund:

Target Description: This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

Gene Symbol: RAD51C

Molekulargewicht: 42190 Da

Gen-ID: 5889

UniProt: O43502

Pathways: DNA Reparatur