ADAM17 Antikörper (C-Term)

Produktnummer ABIN2798820

Dieses Anti-ADAM17-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ADAM17 in WB. Geeignet für Human.

Kurzübersicht für ADAM17 Antikörper (C-Term) (ABIN2798820)

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAM17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ADAM17 Antikörper

Bindungsspezifität: AA 794-823, C-Term

Verwendungszweck: Rabbit Anti-Human ADAM17 (C-term) Antibody

Immunogen: This ADAM17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 794-823 amino acids from the C-terminal region of human ADAM17.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of ADAM17 Antibody (N-term) in Jurkat cell line lysates (35 μg/lane). ADAM17(arrow) was detected using the purified Pab.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu ADAM17

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Andere Bezeichnung: ADAM17

Hintergrund:

Target Description: ADAM17 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM17 functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway.

Gene Symbol: ADAM17

Molekulargewicht: 93021 Da

Gen-ID: 6868

UniProt: P78536

Pathways: Notch Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Response to Growth Hormone Stimulus