KDM5B Antikörper (N-Term)
Kurzübersicht für KDM5B Antikörper (N-Term) (ABIN2798607)
Target
Alle KDM5B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 192-224, N-Term
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Verwendungszweck
- Rabbit Anti-Mouse JARID1B (N-term) Antibody
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Immunogen
- This JARID1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-224 amino acids from the N-terminal region of human JARID1B.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot
Recommended Dilutions
WB: 1:1000JARID1B Antibody (N-term) . -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.410 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
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Andere Bezeichnung
- JARID1B
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Hintergrund
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Target Description: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.
Gene Symbol: KDM5B
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Molekulargewicht
- 175658 Da
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Gen-ID
- 10765
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UniProt
- Q9UGL1
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Pathways
- Warburg Effekt
Target
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