Cyclin D2 Antikörper (N-Term)

Produktnummer ABIN2798589

Dieses Anti-Cyclin D2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cyclin D2 in WB. Geeignet für Human.

Kurzübersicht für Cyclin D2 Antikörper (N-Term) (ABIN2798589)

Target: Cyclin D2 (CCND2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin D2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Cyclin D2 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Verwendungszweck: Rabbit Anti-Human CCND2 (N-term) Antibody

Immunogen: This CCND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCND2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000CCND2 Antibody (N-term) with the CCND2 gene.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu Cyclin D2

Target: Cyclin D2 (CCND2)

Andere Bezeichnung: CCND2

Hintergrund:

Target Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.

Gene Symbol: CCND2

Molekulargewicht: 33067 Da

Gen-ID: 894

UniProt: P30279

Pathways: Zellzyklus, Mitotic G1-G1/S Phases