TERT Antikörper (Center)

Produktnummer ABIN2798432

Der Kaninchen Polyklonal Anti-TERT-Antikörper wurde für WB, FACS und IF validiert. Er ist geeignet, TERT in Proben von Human zu detektieren.

Kurzübersicht für TERT Antikörper (Center) (ABIN2798432)

Target: TERT (Telomerase Reverse Transcriptase (TERT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TERT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-TERT Antikörper

Bindungsspezifität: AA 627-656, Center

Verwendungszweck: Rabbit Anti-Human TERT (Center) Antibody

Immunogen: This TERT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 627-656 amino acids from the Central region of human TERT.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Flow Cytometry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, FC: 1:10-50, IF: 1:10-50Western blot analysis of anti-TERT Antibody (Center) (RB14069) in Jurkat cell line lysates (35 μg/lane). TERT(arrow) was detected using the purified Pab.TERT Antibody (Center) . TERT immunoreactivity is localized to Nucleus significantly and Cytoplasm weakly.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.0 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu TERT

Target: TERT (Telomerase Reverse Transcriptase (TERT))

Andere Bezeichnung: TERT

Hintergrund:

Target Description: Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.

Gene Symbol: TERT

Molekulargewicht: 126997 Da

Gen-ID: 7015

UniProt: O14746

Pathways: Telomere Maintenance