MLH1 Antikörper (Center)

Produktnummer ABIN2797430

Der Kaninchen Polyklonal Anti-MLH1-Antikörper wurde für WB und FACS validiert. Er ist geeignet, MLH1 in Proben von Human zu detektieren.

Kurzübersicht für MLH1 Antikörper (Center) (ABIN2797430)

Target: MLH1 (MutL Homolog 1 (MLH1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-MLH1 Antikörper

Bindungsspezifität: AA 452-480, Center

Verwendungszweck: Rabbit Anti-Human MLH1 (Center) Antibody

Immunogen: This MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-480 amino acids from the Central region of human MLH1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Flow Cytometry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50MLH1 Antibody (Center) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.400 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu MLH1

Target: MLH1 (MutL Homolog 1 (MLH1))

Andere Bezeichnung: MLH1

Hintergrund:

Target Description: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

Gene Symbol: MLH1

Molekulargewicht: 84601 Da

Gen-ID: 4292

UniProt: P40692

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response