KISS1 Antikörper (Center)

Produktnummer ABIN2796067

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KISS1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für KISS1 Antikörper (Center) (ABIN2796067)

Target: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KISS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KISS1 Antikörper

Bindungsspezifität: AA 235-263, Center

Verwendungszweck: Rabbit Anti-Human KISS1R (Center) Antibody

Immunogen: This KISS1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-263 amino acids from the Central region of human KISS1R.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000KISS1R Antibody (Center) .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.650 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu KISS1

Target: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Andere Bezeichnung: KISS1

Hintergrund:

Target Description: Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

Gene Symbol: KISS1R

Molekulargewicht: 42586 Da

Gen-ID: 84634

UniProt: Q969F8

Pathways: Positive Regulation of Peptide Hormone Secretion