APC Antikörper (Center) (APC)
Kurzübersicht für APC Antikörper (Center) (APC) (ABIN2795685)
Target
Alle APC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1148-1176, Center
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Verwendungszweck
- Rabbit Anti-Mouse APC (Center) Antibody
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Immunogen
- This APC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1148-1176 amino acids from the Central region of human APC.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot
Recommended Dilutions
WB: 1:1000APC Antibody (Center). -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- APC (Adenomatous Polyposis Coli (APC))
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Andere Bezeichnung
- APC
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Hintergrund
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Target Description: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Gene Symbol: APC
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Molekulargewicht
- 311646 Da
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Gen-ID
- 324
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UniProt
- P25054
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Pathways
- WNT Signalweg, Stem Cell Maintenance, Cell-Cell Junction Organization
Target
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