PAK1 Antikörper (pThr423)

Produktnummer ABIN2794204

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PAK1 in IF und DB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PAK1 Antikörper (pThr423) (ABIN2794204)

Target: PAK1 (P21-Activated Kinase 1 (PAK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Dot Blot (DB)

Produktdetails anti-PAK1 Antikörper

Bindungsspezifität: pThr423

Verwendungszweck: Rabbit Anti-Human Phospho-PAK1(T423) Antibody

Immunogen: This PAK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T423 of human PAK1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Immunofluorescence, Dot Blot
Recommended Dilutions
IF: 1:10-50, DB: 1:500Confocal immunofluorescent analysis of Phospho-PAK1-pT423 Antibody on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 μg per ml.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.460 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu PAK1

Target: PAK1 (P21-Activated Kinase 1 (PAK1))

Andere Bezeichnung: PAK1

Hintergrund:

Target Description: PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology.

Gene Symbol: PAK1

Molekulargewicht: 60647 Da

Gen-ID: 5058

UniProt: Q13153

Pathways: MAPK Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis