NFATC3 Antikörper (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3) (N-Term)

Details for Product anti-NFATC3 Antibody No. ABIN2792685, Anbieter: Anmelden zum Anzeigen
Antigen
  • NFATC3
  • NFATx
  • nf-at
  • nfat4
  • nfatx
  • C80703
  • D8Ertd281e
  • NFAT4
  • NFATX
  • nuclear factor of activated T-cells 3
  • nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
  • nuclear factor of activated T-cells 3 S homeolog
  • NFATC3
  • nfatc3
  • Nfatc3
  • nfatc3.S
Epitop
N-Term
13
5
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Pferd, Human, Maus, Ratte (Rattus)
73
38
4
4
2
1
1
1
1
1
1
1
Wirt
Kaninchen
54
14
5
1
Klonalität
Polyklonal
Konjugat
Dieser NFATC3 Antikörper ist unkonjugiert
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
55
37
22
21
8
5
5
4
3
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human NFATC3
Sequenz AVFPFQYCVE TDIPLKTRKT SEDQAAILPG KLELCSDDQG SLSPARETSI
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Homologie Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 92%
Produktmerkmale This is a rabbit polyclonal antibody against NFATC3. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Plasmids, Primers & others Plasmide, Primers & weitere NFATC3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung NFAT4 / NFATC3 (NFATC3 Antibody Abstract)
Hintergrund NFATC3 is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. NFATC3 plays a role in the regulation of gene expression in T cells and immature thymocytes.The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Four transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: NFAT4, NFATX
Protein Interaction Partner: MAPK9, MAPK8, CDK6, NCOA3, TTF1, CSNK1A1, FOS,
Protein Size: 1068
Molekulargewicht 115 kDa
Gen-ID 4775
NCBI Accession NM_004555, NP_004546
UniProt B5B2S0
Pathways RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Chromatin Binding
Applikations-hinweise WB Suggested Anti-NFATC3 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: Hela cell lysate.
Immunohistochemistry with Thymus tissue at an antibody concentration of 5 µg/mL using anti-NFATC3 antibody (ABIN504679).
Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 1068 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3) (N-Term) antibody (ABIN2792685) WB Suggested Anti-NFATC3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Pos...
Immunohistochemistry (IHC) image for anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3) (N-Term) antibody (ABIN2792685) Immunohistochemistry with Thymus tissue at an antibody concentration of 5µg/ml using ...
Western Blotting (WB) image for anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3) (N-Term) antibody (ABIN2792685) Host: Rabbit Target Name: NFATC3 Sample Type: Fetal Lung lysates Antibody Dilut...
Immunohistochemistry (IHC) image for anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3) (N-Term) antibody (ABIN2792685) Rabbit Anti-NFATC3 Antibody Paraffin Embedded Tissue: Human alveolar cell Ce...
Western Blotting (WB) image for anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3) (N-Term) antibody (ABIN2792685) Host: Mouse Target Name: NFATC3 Sample Tissue: Mouse Pancreas Antibody Dilution...
Allgemeine Veröffentlichungen Manley, Ohara, Gee, Simkevich, Sedivy, Atwood: "NFAT4 is required for JC virus infection of glial cells." in: Journal of virology, Vol. 80, Issue 24, pp. 12079-85, 2006 (PubMed).

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