LMO2 Antikörper (N-Term)

Produktnummer ABIN2792668

Dieses Anti-LMO2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LMO2 in WB. Geeignet für Maus, Ratte, Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für LMO2 Antikörper (N-Term) (ABIN2792668)

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Reaktivität: Maus, Ratte, Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LMO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LMO2 Antikörper

Bindungsspezifität: N-Term

Sequenz: GGGARAPEGV RAPAAGQPRA TKGAPPPPGT PPPSPMSSAI ERKSLDPSEE

Kreuzreaktivität: Rind (Kuh), Huhn, Human, Maus, Ratte (Rattus)

Homologie: Dog: 100%, Guinea Pig: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LMO2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LMO2

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-LMO2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: Human kidney.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 158 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu LMO2

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Andere Bezeichnung: Rhombotin-2

Hintergrund: LMO2 acts with TAL1/SCL to regulate red blood cell development. LMO2 also acts with LDB1 to maintain erythroid precursors in an immature state.LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RBTN2, RBTNL1, RHOM2, TTG2
Protein Interaction Partner: ADAMTSL4, MBIP, HOOK1, TFPT, NOTCH2NL, KRTAP10-7, CCDC36, NUTM1, SPERT, FAM154A, CLHC1, KRT40, SSX2IP, CMTM5, MRFAP1L1, IFT43, C1orf94, LZTS2, TSC22D4, DBF4B, CCDC33, RINT1, NIF3L1, TRIM54, AGTRAP, ZFP64, BANP, STAT3, STAT1, SOX5, SKP1, ROCK1, REL, PRKG1,
Protein Size: 158

Molekulargewicht: 18 kDa

Gen-ID: 4005

NCBI Accession: NM_005574, NP_005565

UniProt: P25791

Pathways: Chromatin Binding