Rekombinanter LMO2 Antikörper (AA 23-140)

Produktnummer ABIN6939967

Der Maus Monoklonal anti-LMO2 Antikörper wird verwendet zum Nachweis von LMO2 in Proben von Human. Er wurde validiert für WB, IHC und FACS.

Kurzübersicht für Rekombinanter LMO2 Antikörper (AA 23-140) (ABIN6939967)

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LMO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: RLMO2-1971

Produktdetails anti-LMO2 Antikörper

Bindungsspezifität: AA 23-140

Verwendungszweck: Recombinant LMO2 (B-Cell Marker) Antibody

Spezifität: The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin.LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human LMO2 protein fragment (around aa 23-140) (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: K562, Ramos or Raji cells. Placenta, pancreas or Hodgkin s lymphoma.

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu LMO2

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Andere Bezeichnung: LMO2

Hintergrund:

Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, RBTN L1, RBTN2,Rhombotinlike 1, Rhombotin-2 (RHOM2), T-cell translocation protein 2, TTG2

K562, Hodgkin s lymphoma., Ramos or Raji cells.Human placenta, pancreas, Brain

Molekulargewicht: 24kDa

Gen-ID: 4005, 34560

UniProt: P25791

Pathways: Chromatin Binding