Id2 Antikörper (Middle Region)

Produktnummer ABIN2792664

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Id2 in IHC und WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Rind (Kuh) und Schwein.

Kurzübersicht für Id2 Antikörper (Middle Region) (ABIN2792664)

Target: Id2 (Inhibitor of DNA Binding 2 (Id2))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Id2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails anti-Id2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: TIVSLHHQRP GQNQASRTPL TTLNTDISIL SLQASEFPSE LMSNDSKALC

Kreuzreaktivität: Rind (Kuh), Huhn, Human, Maus, Schwein, Ratte (Rattus)

Homologie: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ID2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ID2

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-ID2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: Human Thymus.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 134 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Id2

Target: Id2 (Inhibitor of DNA Binding 2 (Id2))

Andere Bezeichnung: ID2 / BHLHB26

Hintergrund: ID2 belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation.The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GIG8, ID2A, ID2H, MGC26389, bHLHb26
Protein Interaction Partner: ASB4, UBC, SUV39H2, PRMT6, KDM1A, SUV39H1, TCF12, TCF3, TSTA3, MAPK8, ID2, HSPA5, RBL2, RBL1, RB1, CDK2, USP1, MAPK3, MAPK1, E2F4, SIN3A, GATA4, NKX2-5, LRIF1, PPP1CA, RBM48, NEDD9, UNC119, MSC, TCF4, ELK3, ELK4, ELK1, PAX8, PAX5, PAX2, MYF6, MYF5, MYOG,
Protein Size: 134

Molekulargewicht: 15 kDa

Gen-ID: 3398

NCBI Accession: NM_002166, NP_002157

UniProt: Q02363