Id2 Antikörper (Middle Region)

Produktnummer ABIN2792664

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Id2 in IHC und WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Rind (Kuh) und Schwein.

Kurzübersicht für Id2 Antikörper (Middle Region) (ABIN2792664)

Target: Id2 (Inhibitor of DNA Binding 2 (Id2))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Id2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails anti-Id2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: TIVSLHHQRP GQNQASRTPL TTLNTDISIL SLQASEFPSE LMSNDSKALC

Kreuzreaktivität: Rind (Kuh), Huhn, Human, Maus, Schwein, Ratte (Rattus)

Homologie: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ID2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ID2

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-ID2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: Human Thymus.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 134 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Id2

Target: Id2 (Inhibitor of DNA Binding 2 (Id2))

Andere Bezeichnung: ID2 / BHLHB26

Hintergrund: ID2 belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation.The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GIG8, ID2A, ID2H, MGC26389, bHLHb26
Protein Interaction Partner: ASB4, UBC, SUV39H2, PRMT6, KDM1A, SUV39H1, TCF12, TCF3, TSTA3, MAPK8, ID2, HSPA5, RBL2, RBL1, RB1, CDK2, USP1, MAPK3, MAPK1, E2F4, SIN3A, GATA4, NKX2-5, LRIF1, PPP1CA, RBM48, NEDD9, UNC119, MSC, TCF4, ELK3, ELK4, ELK1, PAX8, PAX5, PAX2, MYF6, MYF5, MYOG,
Protein Size: 134

Molekulargewicht: 15 kDa

Gen-ID: 3398

NCBI Accession: NM_002166, NP_002157

UniProt: Q02363