MYBL2 Antikörper (N-Term)

Produktnummer ABIN2792568

Der Kaninchen Polyklonal Anti-MYBL2 Antikörper wurde für WB und IHC validiert. Er ist geeignet, MYBL2 in Proben von Human, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio) zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für MYBL2 Antikörper (N-Term) (ABIN2792568)

Target: MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

Reaktivität: Human, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYBL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MYBL2 Antikörper

Bindungsspezifität: N-Term

Sequenz: RCEDLDELHY QDTDSDVPEQ RDSKCKVKWT HEEDEQLRAL VRQFGQQDWK

Kreuzreaktivität: Rind (Kuh), Hund, Huhn, Human, Ratte (Rattus)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Rabbit: 92%, Rat: 78%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against MYBL2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MYBL2

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-MYBL2 Antibody Titration: 0.2-1 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 700 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-MYBL2 Antikörper (ABIN2792568)

Tashiro, Sumi, Uozumi, Shimizu, Nakamura: "B-Myb-dependent regulation of c-Myc expression by cytosolic phospholipase A2." in: The Journal of biological chemistry, Vol. 279, Issue 17, pp. 17715-22, (2004) (PubMed).

Details zu MYBL2

Target: MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

Andere Bezeichnung: MYBL2

Hintergrund: Myb-Related Protein B (MYBL2), a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.
Alias Symbols: BMYB, B-MYB
Protein Interaction Partner: CCNA1, CDK2, CCNE1, LIN54, SPTBN1, SPTA1, FLNA, CLTC, CLTA, LIN9, UBE2D4, CXCR4, LIN52, LIN37, RBL1, RBBP4, SUMO2, MAP1LC3B, MAPK6, NLK, HIPK2, CREBBP, ZBTB9, TRIM15, LZTR1, CDK9, ZNF622, UBB, TTF2, EP300, SND1, SKP2, MYBL2, NCOR1, NCOR2, PARP1, CCND1, CC
Protein Size: 700

Molekulargewicht: 79 kDa

Gen-ID: 4605

NCBI Accession: NM_002466, NP_002457

UniProt: P10244

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, Chromatin Binding