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SMAD3 Antikörper (N-Term)

Name: SMAD3 Antikörper (N-Term)
SKU: ABIN2792537
Price: 457.44 EUR
Availability: InStock

SMAD3 Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated

WB Suggested Anti-SMAD3 Antibody Titration: 2.

IHC

Host: Mouse Target Name: SMAD3 Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml

Rabbit Anti-SMAD3 Antibody Formalin Fixed Paraffin Embedded Tissue: Human Urinary Bladder Tissue Observed Staining: Cytoplasm Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.

IHC

4 Abbildungen

Produktnummer ABIN2792537

Datenblatt (PDF)

Target Alle SMAD3 Antikörper anzeigen

SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
Bindungsspezifität
34

29

28

28

20

14

14

11

11

9

8

7

6

6

5

5

4

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reaktivität
256

149

137

28

10

9

7

7

7

5

4

3

3

1

1

1

1
Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Meerschweinchen
Wirt
247

23
Kaninchen
Passende Sekundärantikörper
Klonalität
230

40
Polyklonal
Konjugat
137

19

14

14

12

8

6

6

6

6

6

6

4

4

4

4

4

2

2

2

2

2
Dieser SMAD3 Antikörper ist unkonjugiert
Applikation
230

117

107

74

59

55

55

53

28

13

10

8

5

4

2

1
Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz

FTPPIVKRLL GWKKGEQNGQ EEKWCEKAVK SLVKKLKKTG QLDELEKAIT

Kreuzreaktivität

Hund, Huhn, Human, Maus, Schwein, Ratte (Rattus)

Homologie

Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale

This is a rabbit polyclonal antibody against SMAD3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung

Protein A purified

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD3

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anti-SMAD, Mothers Against DPP Homolog 3 (SMAD3) (AA 186-215) antibody
SMAD3 Reaktivität: Human, Maus WB, IHC (p), IF, FACS Wirt: Kaninchen Polyclonal RB24758 unconjugated

anti-SMAD, Mothers Against DPP Homolog 3 (SMAD3) antibody
SMAD3 Reaktivität: Human, Maus, Ratte WB, IHC (p), FACS, IF (cc) Wirt: Kaninchen Monoclonal 3D1 unconjugated

Applikationshinweise

WB Suggested Anti-SMAD3 Antibody Titration: 2.0 µg/mL
Positive Control: Human Liver.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare

Antigen size: 425 AA

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freeze-thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target

SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Andere Bezeichnung

SMAD3 (SMAD3 Produkte)

Hintergrund

SMAD3 is a member of Smad family proteins. SMAD family is known to be important cytoplasmic mediators of signals from the transforming growth factor-beta (TGF-beta) receptor serine/threonine kinases.
Alias Symbols: LDS1C, MADH3, JV15-2, HSPC193, HsT17436
Protein Interaction Partner: TEKT4, CCDC33, CPSF7, MEOX2, HDAC1, PHC2, WWP1, AES, BLZF1, UBC, TP53, SMAD4, BACH1, MAFK, FOXO3, NEDD8, TRIM33, WWP2, SMURF2, FOXM1, TRIM62, TP63, OTUB1, NEDD4L, BAG3, TGFB1I1, CSNK1D, RUNX1, HCVgp1, TSC2, FHL3, FHL2, FHL1, Melk, IRF7, RNF111, LCK, KLF5,
Protein Size: 425

Molekulargewicht

48 kDa

Gen-ID

4088

NCBI Accession

NM_005902, NP_005893

UniProt

Q92940

Pathways

Zellzyklus, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagie