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VEGFR2/CD309 Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-VEGFR2/CD309-Antikörper wurde für WB und IHC validiert. Er ist geeignet, VEGFR2/CD309 in Proben von Human, Schwein, Hund, Rind (Kuh) und Pferd zu detektieren.
Produktnummer ABIN2792307

Kurzübersicht für VEGFR2/CD309 Antikörper (N-Term) (ABIN2792307)

Target

Alle VEGFR2/CD309 (VEGFR2) Antikörper anzeigen
VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reaktivität

  • 329
  • 212
  • 145
  • 17
  • 10
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Schwein, Hund, Rind (Kuh), Pferd

Wirt

  • 299
  • 73
  • 35
  • 4
  • 1
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 290
  • 125
Polyklonal

Konjugat

  • 187
  • 36
  • 21
  • 14
  • 11
  • 9
  • 9
  • 8
  • 7
  • 7
  • 7
  • 7
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser VEGFR2/CD309 Antikörper ist unkonjugiert

Applikation

  • 233
  • 130
  • 120
  • 118
  • 66
  • 42
  • 42
  • 26
  • 26
  • 16
  • 13
  • 13
  • 9
  • 7
  • 7
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 37
    • 34
    • 27
    • 23
    • 20
    • 16
    • 16
    • 13
    • 13
    • 11
    • 10
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    LNVGIDFNWE YPSSKHQHKK LVNRDLKTQS GSEMKKFLST LTIDGVTRSD

    Homologie

    Cow: 86%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against KDR. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human KDR
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 1356 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

    Andere Bezeichnung

    KDR

    Hintergrund

    KDR is the receptor for VEGF or VEGFC. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
    Alias Symbols: CD309, FLK1, VEGFR, VEGFR2
    Protein Interaction Partner: FBXO25, VEGFA, MYO1C, CAV1, NPM1, EPN1, SRC, CBL, IQGAP1, UBC, CSNK1D, FBXW11, BTRC, CUL1, AIMP2, SHC2, SYNGAP1, ACP1, ATR, FRS2, SH2D2A, DNM2, NRP1, VEGFC, GRB10, CDH5, GNAQ, SHC1, STAT1, NCK1, SHB, PLCG2, P2RY2, BMX, FIGF, KDR, TIMP3, PTPN6, PTPN11, ITG
    Protein Size: 1356

    Molekulargewicht

    151 kDa

    Gen-ID

    3791

    NCBI Accession

    NM_002253, NP_002244

    UniProt

    P35968

    Pathways

    RTK Signalweg, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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