VEGFR2/CD309 Antikörper (N-Term)
Kurzübersicht für VEGFR2/CD309 Antikörper (N-Term) (ABIN2792307)
Target
Alle VEGFR2/CD309 (VEGFR2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- LNVGIDFNWE YPSSKHQHKK LVNRDLKTQS GSEMKKFLST LTIDGVTRSD
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Homologie
- Cow: 86%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against KDR. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human KDR
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 1356 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
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Andere Bezeichnung
- KDR
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Hintergrund
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KDR is the receptor for VEGF or VEGFC. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Alias Symbols: CD309, FLK1, VEGFR, VEGFR2
Protein Interaction Partner: FBXO25, VEGFA, MYO1C, CAV1, NPM1, EPN1, SRC, CBL, IQGAP1, UBC, CSNK1D, FBXW11, BTRC, CUL1, AIMP2, SHC2, SYNGAP1, ACP1, ATR, FRS2, SH2D2A, DNM2, NRP1, VEGFC, GRB10, CDH5, GNAQ, SHC1, STAT1, NCK1, SHB, PLCG2, P2RY2, BMX, FIGF, KDR, TIMP3, PTPN6, PTPN11, ITG
Protein Size: 1356 -
Molekulargewicht
- 151 kDa
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Gen-ID
- 3791
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NCBI Accession
- NM_002253, NP_002244
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UniProt
- P35968
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Pathways
- RTK Signalweg, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
Target
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