HTR2A Antikörper (N-Term)

Produktnummer ABIN2792273

Der Kaninchen Polyklonal anti-HTR2A Antikörper (ABIN2792273) detektiert spezifisch HTR2A in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Schwein.

Kurzübersicht für HTR2A Antikörper (N-Term) (ABIN2792273)

Target: HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

Reaktivität: Human, Maus, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTR2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HTR2A Antikörper

Bindungsspezifität: N-Term

Sequenz: DILCEENTSL SSTTNSLMQL NDDTRLYSND FNSGEANTSD AFNWTVDSEN

Homologie: Human: 100%, Mouse: 78%, Pig: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against HTR2A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HTR2A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 471 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HTR2A

Target: HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

Andere Bezeichnung: HTR2A

Hintergrund: HTR2A belongs to the G-protein coupled receptor 1 family. It is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
Alias Symbols: 5-HT2A, HTR2
Protein Interaction Partner: LYN, CBL, NDUFB10, ANKS1B, MRPL28, EIF3F, DLG4, PON2, NME3, GNAQ, PPP5C, MAP1A, RPS6KA3, NTRK3, JAK2, GNA11, GNAI1, GLUL,
Protein Size: 471

Molekulargewicht: 52 kDa

Gen-ID: 3356

NCBI Accession: NM_000621, NP_000612

UniProt: P28223

Pathways: JAK-STAT Signalweg, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process