HTR2A Antikörper (AA 65-160)

Produktnummer ABIN737016

Produktdetails anti-HTR2A Antikörper

Target: HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

Bindungsspezifität: AA 65-160

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTR2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5-HTR2A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-HTR2A Antikörper (ABIN737016)

Sun, Wang, Huang, Cao: "Antihypertensive effect of formononetin through regulating the expressions of eNOS, 5-HT2A/1B receptors and ?1-adrenoceptors in spontaneously rat arteries." in: European journal of pharmacology, Vol. 699, Issue 1-3, pp. 241-9, (2013) (PubMed).

Details zu HTR2A

Target: HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

Andere Bezeichnung: 5-HTR2 (HTR2A Produkte)

Synonyme: 5-HT2A antikoerper, HTR2 antikoerper, 5-HT-2 antikoerper, 5-HT-2A antikoerper, 5-HTR2A antikoerper, LOC100009461 antikoerper, E030013E04 antikoerper, Htr-2 antikoerper, Htr2 antikoerper, 5Ht-2 antikoerper, 5HT2A antikoerper, 5HTR2A antikoerper, HTR2A antikoerper, Htr2a antikoerper, 5HT2 antikoerper, 5-hydroxytryptamine receptor 2A antikoerper, 5-hydroxytryptamine (serotonin) receptor 2A antikoerper, HTR2A antikoerper, Htr2a antikoerper

Hintergrund:

Synonyms: HTR2, 5-HT2A, 5-hydroxytryptamine receptor 2A, 5-HT-2, 5-HT-2A, Serotonin receptor 2A, HTR2A

Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.

Gen-ID: 3356

UniProt: P28223

Pathways: JAK-STAT Signalweg, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process