SFRP1 Antikörper (Middle Region)
Kurzübersicht für SFRP1 Antikörper (Middle Region) (ABIN2792235)
Target
Alle SFRP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- SFRP1 Antibody - middle region
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Sequenz
- HQLDNLSHHF LIMGRKVKSQ YLLTAIHKWD KKNKEFKNFM KKMKNHECPT
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SFRP1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SFRP1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Involvement of genetic instability in the downregulation of sFRP1 in Chinese patients with hepatocellular carcinoma." in: Anatomical record (Hoboken, N.J. : 2007), Vol. 293, Issue 12, pp. 2020-6, (2010) (PubMed).
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- SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
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Andere Bezeichnung
- SFRP1
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Hintergrund
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Background Information: Secreted frizzled-related protein 1 (SFRP1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 may be involved in de
Gene Name: Secreted frizzled-related protein 1
Alternative Symbols: FRP, FRP1, FrzA, FRP-1, SARP2
Protein Name: Secreted frizzled-related protein 1
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Molekulargewicht
- 35kDa
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Gen-ID
- 6422
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NCBI Accession
- NP_003003
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UniProt
- Q8N474
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Pathways
- WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation
Target
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