SFRP1 Antikörper (Middle Region)

Produktnummer ABIN2792235

Produktdetails anti-SFRP1 Antikörper

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SFRP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HQLDNLSHHF LIMGRKVKSQ YLLTAIHKWD KKNKEFKNFM KKMKNHECPT

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SFRP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SFRP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 314 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SFRP1 Antikörper (ABIN2792235)

Qiu, Xu, Zhou, Shi, Ma, Li, Li: "Involvement of genetic instability in the downregulation of sFRP1 in Chinese patients with hepatocellular carcinoma." in: Anatomical record (Hoboken, N.J. : 2007), Vol. 293, Issue 12, pp. 2020-6, (2010) (PubMed).

Details zu SFRP1

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Andere Bezeichnung: SFRP1 (SFRP1 Produkte)

Hintergrund: Secreted frizzled-related protein 1 (SFRP1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 may be involved in de
Alias Symbols: FRP, FRP1, FrzA, FRP-1, SARP2
Protein Interaction Partner: KIAA1522, PPP1CC, PPP1CA, WNT4, FZD6, WNT1, WNT2,
Protein Size: 314

Molekulargewicht: 35 kDa

Gen-ID: 6422

NCBI Accession: NM_003012, NP_003003

UniProt: Q8N474

Pathways: WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation