HSPD1 Antikörper (C-Term)

Produktnummer ABIN2792215

Dieses Anti-HSPD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HSPD1 in WB. Geeignet für Human, Ratte, Kaninchen und Meerschweinchen.

Kurzübersicht für HSPD1 Antikörper (C-Term) (ABIN2792215)

Target: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Reaktivität: Human, Ratte, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HSPD1 Antikörper

Bindungsspezifität: C-Term

Sequenz: PTKVVRTALL DAAGVASLLT TAEVVVTEIP KEEKDPGMGA MGGMGGGMGG

Homologie: Guinea Pig: 90%, Human: 84%, Rabbit: 84%, Rat: 84%

Produktmerkmale: This is a rabbit polyclonal antibody against HSPD1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HSPD1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 573 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HSPD1

Target: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Andere Bezeichnung: HSPD1

Hintergrund: HSPD1 is a member of the chaperonin family. This mitochondrial protein may function as a signaling molecule in the innate immune system. It is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
Alias Symbols: CPN60, GROEL, HSP60, HSP65, HuCHA60, SPG13, HLD4, HSP-60
Protein Interaction Partner: RGS20, NOTCH2NL, KRTAP10-3, KRTAP10-8, SAMD3, KRT40, LZTS2, CEP70, HUWE1, TMCC2, KRT31, KRTAP5-9, FUS, TUBGCP3, AURKB, VCP, UBC, TUBG1, AURKA, SUMO3, LGALS3BP, CDC20, STAU1, LGR4, NEDD8, MDM2, ERG, ASB4, EED, MAPK14, ATP6V1A, RAB1B, C12orf10, NAGK, C11orf
Protein Size: 573

Molekulargewicht: 61 kDa

Gen-ID: 3329

NCBI Accession: NM_002156, NP_002147

UniProt: P10809

Pathways: Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity