RBX1 Antikörper (Middle Region)

Produktnummer ABIN2792171

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RBX1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio) und Meerschweinchen und wurde in 1 Publikation erwähnt.

Kurzübersicht für RBX1 Antikörper (Middle Region) (ABIN2792171)

Target: RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RBX1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: NQASATSEEC TVAWGVCNHA FHFHCISRWL KTRQVCPLDN REWEFQKYGH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RBX1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RBX1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 108 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RBX1 Antikörper (ABIN2792171)

Maerki, Olma, Staubli, Steigemann, Gerlich, Quadroni, Sumara, Peter: "The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis." in: The Journal of cell biology, Vol. 187, Issue 6, pp. 791-800, (2009) (PubMed).

Details zu RBX1

Target: RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1))

Andere Bezeichnung: RBX1

Hintergrund: ROC1 encodes an evolutionarily conserved protein that interacts with cullins. The protein plays a unique role in the ubiquitination reaction by heterodimerizing with cullin-1 to catalyze ubiquitin polymerization. It also may be involved in the regulation of protein turn-over.
Alias Symbols: ROC1, RNF75, BA554C12.1
Protein Interaction Partner: CDT1, CDC34, KEAP1, UBE2L6, UBE2M, CUL1, CUL3, CUL4B, UBE2D3, UBE2D2, UBE2D1, DAB2IP, UBC, TP53, PRAME, DCUN1D1, CUL2, DCUN1D3, MAP4K1, VHL, NEDD4, MTSS1, VRK2, HIST1H4A, GFPT1, CTNNB1, CCNE1, DCUN1D5, FBXL5, RHOBTB3, SAMHD1, UBC12, FBXL15, UBE2R2, SERTAD
Protein Size: 108

Molekulargewicht: 12 kDa

Gen-ID: 9978

NCBI Accession: NM_014248, NP_055063

UniProt: P62877

Pathways: Zellzyklus, M Phase, SARS-CoV-2 Protein Interaktom