RBX1 Antikörper (Middle Region)

Produktnummer ABIN2792171

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch RBX1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio) und Meerschweinchen und wurde in 1 Publikation erwähnt.

Kurzübersicht für RBX1 Antikörper (Middle Region) (ABIN2792171)

Target: RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RBX1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: NQASATSEEC TVAWGVCNHA FHFHCISRWL KTRQVCPLDN REWEFQKYGH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RBX1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RBX1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 108 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RBX1 Antikörper (ABIN2792171)

Maerki, Olma, Staubli, Steigemann, Gerlich, Quadroni, Sumara, Peter: "The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis." in: The Journal of cell biology, Vol. 187, Issue 6, pp. 791-800, (2009) (PubMed).

Details zu RBX1

Target: RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1))

Andere Bezeichnung: RBX1

Hintergrund: ROC1 encodes an evolutionarily conserved protein that interacts with cullins. The protein plays a unique role in the ubiquitination reaction by heterodimerizing with cullin-1 to catalyze ubiquitin polymerization. It also may be involved in the regulation of protein turn-over.
Alias Symbols: ROC1, RNF75, BA554C12.1
Protein Interaction Partner: CDT1, CDC34, KEAP1, UBE2L6, UBE2M, CUL1, CUL3, CUL4B, UBE2D3, UBE2D2, UBE2D1, DAB2IP, UBC, TP53, PRAME, DCUN1D1, CUL2, DCUN1D3, MAP4K1, VHL, NEDD4, MTSS1, VRK2, HIST1H4A, GFPT1, CTNNB1, CCNE1, DCUN1D5, FBXL5, RHOBTB3, SAMHD1, UBC12, FBXL15, UBE2R2, SERTAD
Protein Size: 108

Molekulargewicht: 12 kDa

Gen-ID: 9978

NCBI Accession: NM_014248, NP_055063

UniProt: P62877

Pathways: Zellzyklus, M Phase, SARS-CoV-2 Protein Interaktom