PREX2 Antikörper (N-Term)

Produktnummer ABIN2498288

Produktdetails anti-PREX2 Antikörper

Target: PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PREX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ERDYVGTLEF LVSAFLHRMN QCAASKVDKN VTEETVKMLF SNIEDILAVH

Homologie: Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PREX2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PREX2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PREX2

Target: PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))

Andere Bezeichnung: PREX2 (DEPDC2 Produkte)

Hintergrund: PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. PREX2 mediates the activation of RAC1 in a PI3K-dependent manner. PREX2 may be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
Protein Interaction Partner: PPP1CA, MTOR, TGFBR1,
Protein Size: 1606

Molekulargewicht: 182 kDa

Gen-ID: 80243

UniProt: Q70Z35