PREX2 Antikörper (N-Term)

Produktnummer ABIN2791874

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PREX2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für PREX2 Antikörper (N-Term) (ABIN2791874)

Target: PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PREX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PREX2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PREX2 Antibody - N-terminal region

Sequenz: ERDYVGTLEF LVSAFLHRMN QCAASKVDKN VTEETVKMLF SNIEDILAVH

Homologie: Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PREX2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PREX2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP71437-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PREX2

Target: PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))

Andere Bezeichnung: PREX2

Hintergrund:

Background Information: PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. PREX2 mediates the activation of RAC1 in a PI3K-dependent manner. PREX2 may be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.

Alternative Symbols: DEP.2, DEPDC2, P-REX2, PPP1R129

Molekulargewicht: 182kDa

Gen-ID: 80243

UniProt: Q70Z35