FAK Antikörper (Middle Region)

Produktnummer ABIN2791666

Dieses Anti-FAK-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FAK in WB. Geeignet für Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Kaninchen, Rind (Kuh), Pferd und Meerschweinchen.

Kurzübersicht für FAK Antikörper (Middle Region) (ABIN2791666)

Target: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FAK Antikörper

Bindungsspezifität: Middle Region

Sequenz: SEKQGMRTHA VSVSETDDYA EIIDEEDTYT MPSTRDYEIQ RER
IELGRC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PTK2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PTK2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FAK

Target: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Andere Bezeichnung: PTK2

Hintergrund: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Protein Interaction Partner: DEF6, SOCS3, YES1, IQGAP1, UBE2H, UBC, TRIM72, SRPK1, PXN, PTRH2, SAE1, HSP90AA1, APP, RBSN, BCAR1, KCNJ3, PTAFR, STAT1, CBL, STAP2, STUB1, PTPN11, PPP1CB, PPP1CA, SRC, CTTN, ASAP1, SH3KBP1, PDCD6IP, ITGB5, ELAVL1, DAG1, GRB2, FBP1, F13A1, EEF1G, LPXN, TG
Protein Size: 431

Molekulargewicht: 47 kDa

Gen-ID: 5747

Pathways: Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling