REPS2 Antikörper (C-Term)

Produktnummer ABIN2499755

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch REPS2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Schwein.

Kurzübersicht für REPS2 Antikörper (C-Term) (ABIN2499755)

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser REPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-REPS2 Antikörper

Bindungsspezifität: C-Term

Sequenz: KDVLYSQPPS KPIRRKFRPE NQATENQEPS TAASGPASAA TMKPHPTVQK

Homologie: Cow: 100%, Dog: 80%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 83%, Pig: 100%, Rabbit: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against REPS2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human REPS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu REPS2

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Andere Bezeichnung: REPS2

Hintergrund: The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: EPN1, CDK1, AP2A1, GRB2, AMPH, AR, CDK5RAP2, REPS1, RALBP1, EPS15, ASAP1, ASAP2, PXN, RALB, RELA,
Protein Size: 521

Molekulargewicht: 57 kDa

Gen-ID: 9185

Pathways: EGFR Signaling Pathway