REPS2 Antikörper (N-Term)

Produktnummer ABIN657055

Produktdetails anti-REPS2 Antikörper

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Bindungsspezifität: AA 153-182, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser REPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This REPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the N-terminal region of human REPS2.

Klon: RB32411

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu REPS2

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Andere Bezeichnung: REPS2 (REPS2 Produkte)

Synonyme: POB1 antikoerper, RALBP1 associated Eps domain containing 2 antikoerper, RALBP1 associated Eps domain containing protein 2 antikoerper, REPS2 antikoerper, Reps2 antikoerper

Hintergrund: The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 71534

NCBI Accession: NP_001074444, NP_004717

UniProt: Q8NFH8

Pathways: EGFR Signaling Pathway