REPS2 Antikörper (AA 390-470)

Produktnummer ABIN7230998

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch REPS2 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für REPS2 Antikörper (AA 390-470) (ABIN7230998)

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser REPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-REPS2 Antikörper

Bindungsspezifität: AA 390-470

Verwendungszweck: Rabbit Anti-REPS2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of REPS2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human REPS2 protein at AA range: 390-470

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu REPS2

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Andere Bezeichnung: REPS2

Hintergrund: RalBP1-associated Eps domain-containing protein 2, Partner of RalBP1, RalBP1-interacting protein 2The product of REPS2 (RALBP1 Associated Eps Domain Containing 2) is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for REPS2.

Molekulargewicht: 72kD

Gen-ID: 9185

UniProt: Q8NFH8

Pathways: EGFR Signaling Pathway