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MMP25 Antikörper (Middle Region)

MMP25 Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2789901
  • Target Alle MMP25 Antikörper anzeigen
    MMP25 (Matrix Metallopeptidase 25 (MMP25))
    Bindungsspezifität
    • 9
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen
    Wirt
    • 37
    • 2
    Kaninchen
    Klonalität
    • 37
    • 2
    Polyklonal
    Konjugat
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser MMP25 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 16
    • 9
    • 7
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    FGHALGLGHS SAPNSIMRPF YQGPVGDPDK YRLSQDDRDG LQQLYGKAPQ
    Homologie
    Dog: 82%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against MMP25. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Top Product
    Discover our top product MMP25 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 562 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MMP25 (Matrix Metallopeptidase 25 (MMP25))
    Andere Bezeichnung
    MMP25 (MMP25 Produkte)
    Synonyme
    MMP-25 antikoerper, MMP20 antikoerper, MMP20A antikoerper, MMPL1 antikoerper, MT-MMP 6 antikoerper, MT-MMP6 antikoerper, MT6-MMP antikoerper, MT6MMP antikoerper, MTMMP6 antikoerper, F730048C11Rik antikoerper, Leukolysin antikoerper, matrix metallopeptidase 25 antikoerper, MMP25 antikoerper, Mmp25 antikoerper
    Hintergrund
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.
    Alias Symbols: MMP20, MMP20A, MMPL1, MT-MMP6, MT6-MMP
    Protein Interaction Partner: CLU, MMP2,
    Protein Size: 562
    Molekulargewicht
    48 kDa
    Gen-ID
    64386
    NCBI Accession
    NM_022468, NP_071913
    UniProt
    Q9NPA2
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