KRT6A Antikörper (Middle Region)

Produktnummer ABIN2789833

Der Kaninchen Polyklonal Anti-KRT6A-Antikörper wurde für WB validiert. Er ist geeignet, KRT6A in Proben von Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Schwein, Kaninchen und Schaf zu detektieren.

Kurzübersicht für KRT6A Antikörper (Middle Region) (ABIN2789833)

Target: KRT6A (Keratin 6A (KRT6A))

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Schwein, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KRT6A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KRT6A Antikörper

Bindungsspezifität: Middle Region

Sequenz: RGMQDLVEDF KNKYEDEINK RTAAENEFVT LKKDVDAAYM NKVELQAKAD

Homologie: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against KRT6A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 564 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KRT6A

Target: KRT6A (Keratin 6A (KRT6A))

Andere Bezeichnung: KRT6A

Hintergrund: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Alias Symbols: CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D
Protein Interaction Partner: TRIM54, KRT40, TFIP11, HGS, KRT38, SGTA, KRT31, KRT15, KRT13, KIFC3, GOLGA2, TRIM23, LGR4, EED, KDM1A, PAN2, Iqcb1, Nphp4, Cep290, Nphp1, Invs, UBC, ITGA4, ALB, UBASH3B, SHC1, GRB2, EPS15, CRK, AP2M1, CBL, CUL1, COPS5, CUL2, CUL5, CCDC85B, TCHP, CCDC53, K
Protein Size: 564

Molekulargewicht: 59 kDa

Gen-ID: 3853

NCBI Accession: NM_005554, NP_005545

UniProt: P02538