DUSP4 Antikörper (C-Term)
-
- Target Alle DUSP4 Antikörper anzeigen
- DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
-
Bindungsspezifität
- C-Term
-
Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schwein
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser DUSP4 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- GQLLQFESQV LATSCAAEAA SPSGPLRERG KTPATPTSQF VFSFPVSVGV
- Homologie
- Cow: 92%, Dog: 85%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 85%, Rat: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against DUSP4. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product DUSP4 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 394 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
- Andere Bezeichnung
- DUSP4 (DUSP4 Produkte)
- Synonyme
- zgc:55423 antikoerper, DUSP4 antikoerper, typ antikoerper, hvh2 antikoerper, mkp2 antikoerper, mkp-2 antikoerper, MGC131045 antikoerper, HVH2 antikoerper, MKP-2 antikoerper, MKP2 antikoerper, TYP antikoerper, 2700078F24Rik antikoerper, AI844617 antikoerper, BB104621 antikoerper, E130306H24Rik antikoerper, Mkp-2 antikoerper, Mkp2 antikoerper, dual specificity phosphatase 4 antikoerper, dual specificity phosphatase 4 S homeolog antikoerper, dusp4 antikoerper, DUSP4 antikoerper, dusp4.S antikoerper, Dusp4 antikoerper
- Hintergrund
-
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.
Alias Symbols: HVH2, MKP-2, MKP2, TYP
Protein Interaction Partner: UBC, MAPK8, MAPK3, APP, CRMP1, GRIN1, MAPK9, GRIN2D, MAPK14, MAPK1,
Protein Size: 394 - Molekulargewicht
- 43 kDa
- Gen-ID
- 1846
- NCBI Accession
- NM_001394, NP_001385
- UniProt
- Q13115
- Pathways
- Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
-