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DUSP4 Antikörper (C-Term)

DUSP4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2789728
  • Target Alle DUSP4 Antikörper anzeigen
    DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
    Bindungsspezifität
    • 16
    • 9
    • 8
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 56
    • 34
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schwein
    Wirt
    • 52
    • 4
    Kaninchen
    Klonalität
    • 52
    • 4
    Polyklonal
    Konjugat
    • 24
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DUSP4 Antikörper ist unkonjugiert
    Applikation
    • 49
    • 30
    • 25
    • 14
    • 13
    • 13
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    GQLLQFESQV LATSCAAEAA SPSGPLRERG KTPATPTSQF VFSFPVSVGV
    Homologie
    Cow: 92%, Dog: 85%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 85%, Rat: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against DUSP4. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Top Product
    Discover our top product DUSP4 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 394 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
    Andere Bezeichnung
    DUSP4 (DUSP4 Produkte)
    Synonyme
    zgc:55423 antikoerper, DUSP4 antikoerper, typ antikoerper, hvh2 antikoerper, mkp2 antikoerper, mkp-2 antikoerper, MGC131045 antikoerper, HVH2 antikoerper, MKP-2 antikoerper, MKP2 antikoerper, TYP antikoerper, 2700078F24Rik antikoerper, AI844617 antikoerper, BB104621 antikoerper, E130306H24Rik antikoerper, Mkp-2 antikoerper, Mkp2 antikoerper, dual specificity phosphatase 4 antikoerper, dual specificity phosphatase 4 S homeolog antikoerper, dusp4 antikoerper, DUSP4 antikoerper, dusp4.S antikoerper, Dusp4 antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.
    Alias Symbols: HVH2, MKP-2, MKP2, TYP
    Protein Interaction Partner: UBC, MAPK8, MAPK3, APP, CRMP1, GRIN1, MAPK9, GRIN2D, MAPK14, MAPK1,
    Protein Size: 394
    Molekulargewicht
    43 kDa
    Gen-ID
    1846
    NCBI Accession
    NM_001394, NP_001385
    UniProt
    Q13115
    Pathways
    Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
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