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DUSP4 Antikörper (C-Term)

DUSP4 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB05733 unconjugated
Produktnummer ABIN392861
  • Target Alle DUSP4 Antikörper anzeigen
    DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
    Bindungsspezifität
    • 16
    • 7
    • 7
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 331-361, C-Term
    Reaktivität
    • 56
    • 39
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 52
    • 4
    Kaninchen
    Klonalität
    • 52
    • 4
    Polyklonal
    Konjugat
    • 23
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DUSP4 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 24
    • 20
    • 14
    • 13
    • 13
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This DUSP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the C-terminal region of human DUSP4.
    Klon
    RB05733
    Isotyp
    Ig Fraction
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  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
    Andere Bezeichnung
    DUSP4 (DUSP4 Produkte)
    Synonyme
    zgc:55423 antikoerper, DUSP4 antikoerper, typ antikoerper, hvh2 antikoerper, mkp2 antikoerper, mkp-2 antikoerper, MGC131045 antikoerper, HVH2 antikoerper, MKP-2 antikoerper, MKP2 antikoerper, TYP antikoerper, 2700078F24Rik antikoerper, AI844617 antikoerper, BB104621 antikoerper, E130306H24Rik antikoerper, Mkp-2 antikoerper, Mkp2 antikoerper, dual specificity phosphatase 4 antikoerper, dual specificity phosphatase 4 S homeolog antikoerper, dusp4 antikoerper, DUSP4 antikoerper, dusp4.S antikoerper, Dusp4 antikoerper
    Hintergrund
    DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.
    Molekulargewicht
    42953
    Gen-ID
    1846
    NCBI Accession
    NP_001385, NP_476499
    UniProt
    Q13115
    Pathways
    Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
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