PDE11A Antikörper (N-Term)

Produktnummer ABIN2789716

Der Kaninchen Polyklonal anti-PDE11A Antikörper (ABIN2789716) detektiert spezifisch PDE11A in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio) und Meerschweinchen.

Kurzübersicht für PDE11A Antikörper (N-Term) (ABIN2789716)

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE11A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PDE11A Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PDE11A Antibody - N-terminal region

Sequenz: RRASQKELRK SFARSKAIHV NRTYDEQVTS RAQEPLSSVR RRALLRKASS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PDE11A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64063-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PDE11A

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Andere Bezeichnung: PDE11A

Hintergrund:

Background Information: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Phosphodiesterase 11A

Alternative Symbols: PPNAD2

Protein Name: Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A

Molekulargewicht: 105kDa

Gen-ID: 50940

NCBI Accession: NP_058649

UniProt: Q9HCR9

Pathways: cAMP Metabolic Process